Authors’ Response: Dosage Recommendations for Combination Regimen of Thyroxine and 3,5,3′-Triiodothyronine
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چکیده
منابع مشابه
Thyroxine-triiodothyronine combination therapy versus thyroxine monotherapy for clinical hypothyroidism: meta-analysis of randomized controlled trials.
CONTEXT In some patients symptoms of hypothyroidism persist despite therapy with T(4). OBJECTIVE The objective of the study was to compare the effectiveness of T(4)-T(3) combination vs. T(4) monotherapy for the treatment of clinical hypothyroidism in adults. DATA SOURCES PubMed, EMBASE, LILACS, and the Cochrane Central Register of Controlled Trials (CENTRAL) databases were searched in Septe...
متن کاملThyroxine alone or thyroxine plus triiodothyronine replacement therapy for hypothyroidism.
Standard therapy for patients with hypothyroidism is replacement with synthetic thyroxine (T4). However, thyroxine plus triiodothyronine (T3) replacement therapy resulted in marked improvements in several items of the Profile of Mood States and in a few indices of psychometric function and quality of life. The adequacy of thyroxine alone versus thyroxine plus triiodothyronine to treat hypothyro...
متن کاملThyroxine-protein interactions. Interaction of thyroxine and triiodothyronine with human thyroxine-binding globulin.
The effect of temperature on the binding of thyroxine and triiodothyronine to thyroxine-binding globulin has been studied by equilibrium dialysis. Inclusion of ovalbumin in the dialysis mixture stabilized thyroxine-binding globulin against losses in binding activity which had been found to occur during equilibrium dialysis. Ovalbumin by itself bound the thyroid hormones very weakly and its bind...
متن کاملPeripheral serum thyroxine, triiodothyronine and reverse triiodothyronine kinetics in the low thyroxine state of acute nonthyroidal illnesses. A noncompartmental analysis.
The low thyroxine (T(4)) state of acute critical nonthyroidal illnesses is characterized by marked decreases in serum total T(4) and triiodothyronine (T(3)) with elevated reverse T(3) (rT(3)) values. To better define the mechanisms responsible for these alterations, serum kinetic disappearance studies of labeled T(4), T(3), or rT(3) were determined in 16 patients with the low T(4) state and com...
متن کاملThe effect of baclofen on growth hormone, thyroxine, and triiodothyronine in Holstein cows
In this research study, the effect of baclofen (GABAB receptor agonist) on mean concentration of growth hormone, thyroxine, and triiodothyronine was examined. For this purpose, twelve Holstein Cows were divided into four groups. Then, each cow received daily injection of 25, 50, 75, and l00 mg/kg of baclofen for a period of four days. Blood samples were daily collected at one time point for eig...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2004
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jc.2003-032074